![]() Criteria to define an eye as abnormal were: mfVEP 1) amplitude/latency: either amplitude or latency probability plots meeting cluster criteria with 95% specificity 2) amplitude or latency alone (specificity: 97% and 98%, respectively) HVF and OCT, mean deviation and RNFL thickness meeting p < 0.05, respectively. Methods MfVEP, HVF, and OCT (retinal nerve fiber layer ) were performed in 47 MS-ON eyes (last optic neuritis (ON) attack ≥ 6 months prior) and 65 MS-no-ON eyes without ON history. Frishman, Laura J.īackground Multifocal visual evoked potentials (mfVEP) measure local response amplitude and latency in the field of vision Objective To compare the sensitivity of mfVEP, Humphrey visual field ( HVF) and optical coherence tomography (OCT) in detecting visual abnormality in multiple sclerosis (MS) patients. Laron, Michal Cheng, Han Zhang, Bin Schiffman, Jade S. However, both mfERG and HVF abnormalities were found outside the areas of ophthalmoscopically normal retinal areas.Ĭomparison of multifocal visual evoked potential, standard automated perimetry and optical coherence tomography in assessing visual pathway in multiple sclerosis patients In CACD, in the areas of scotoma detected by HVF, mfERG values were depressed. Similarly, CACD patients had lower P1/N1 amplitudes (p<0.05) and delayed P1/N1 implicit times (p<0.05). The retinal sensitivities in 5 concentric rings in HVF were significantly lower (p<0.001 for ring 1 to ring 4, and p=0.017 in ring 5) in CACD patients. HVF revealed central scotoma in 6 of 7 eyes (85.7%), whereas a paracentral scotoma extending to fixation point was detected in 1 eye. Mean Snellen acuity was 0.49+/-0.10 in patients. The differences between control subjects and patients were evaluated by Mann-Whitney U test and the correlations were assessed by Spearman test. HVF results were evaluated in 5 concentric rings in order to compare the results to concentric ring analysis in mfERG. mfERG and central 30/2 HVF were tested for each participant. Seven eyes of 4 patients with CACD and 15 normal control subjects were examined. To study multifocal electroretinogram (mfERG) and its relation to retinal sensitivity assessed by Humphrey visual field ( HVF) analysis in central areolar choroidal dystrophy (CACD). Gundogan, Fatih Cakir Dinç, Umut Asli Erdem, Uzeyir Ozge, Gokhan Sobaci, Gungor Multifocal electroretinogram and central visual field testing in central areolar choroidal dystrophy. For permission to use (where not already granted under a licence) please go to Published by the BMJ Publishing Group Limited. Increased test experience or interventions aimed at reducing pretest anxiety may result in improved test reliability and accuracy. Increased pretest anxiety may reduce HVF test reliability. HVF testing induces more anxiety than HRT. Subjects who had undergone more than 10 visual field tests had significantly lower pretest and intratest anxiety levels than those who had not (p=0.0030 and p=0.0004, respectively). Pretest anxiety was correlated with test unreliability (Spearman's r=0.273, p=0.006), which was predictive of worse test severity (p=0.0027). Within the HVF group, intratest anxiety was 1.2 times higher than pretest anxiety (p=0.0001), but was not significantly different in the HRT group (p=0.145). Trait anxiety (p=0.838) and pretest anxiety (p=0.802) were not significantly different between test groups. ![]() Anxiety scores were used to make non-parametrical comparisons and correlations between cohorts and also against visual field reliability and severity indices. Subjective discomfort parameters were also recorded. A 5-point Likert scale was used to grade pretest anxiety and was repeated after testing to grade intratest anxiety. Prior to testing, participants completed the State-Trait Anxiety Inventory questionnaire. 137 consecutive age-matched and gender-matched patients with glaucoma undergoing either HVF testing only (n=102) or Heidelberg retinal tomography (HRT) only (n=35) were enrolled. A prospective cohort study at a university affiliated private ophthalmic practice. To determine if Humphrey visual field ( HVF) testing induces anxiety and how anxiety relates to visual field parameters of reliability and severity. Chew, Shenton S L Kerr, Nathan M Wong, Aaron B C Craig, Jennifer P Chou, Chi-Ying Danesh-Meyer, Helen V
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